There is boom in stem cell market in recent decade, particularly in the zone of orthopedic and cosmetic applications. Globally, the stem cell therapy is a procedure which is adopted to treat various symptoms, ranging from little injuries to the life-threatening disorders. More than 80 disorders are being treated, using stem cells, around the globe including Unites States. Technically, the stem cell therapy is the replacement of damaged or injured cells with functional and healthy cells. It sounds new and simple applications with broad benefits.
Below is the list of some disorders which are being treated with the stem cell therapy in the globe including United States:
- Eyes diseases
- Spinal cord Injuries
- Parkinson’s disease
- Many more…
The stem cell therapy is performed through various procedures depending on the type of diseases, includes:
- Stem cell therapy using bone marrow stem cells
- Stem cell therapy using peripheral stem cells
- Stem cell therapy using umbilical cord blood
- Stem cell therapy using therapeutic cloning
Though the stem cell therapy is living in its neonatal stages and researchers are doing their experimental work in USA and other parts of the world but a promising atmosphere is spreading all over the world in the treatment of various life-threatening diseases.
The patients of Leukaemia and other cancers are going under replacement of blood cells using bone marrow stem cell therapy. Skin-burned patients are treated using stem cell therapies and their burned cells are grafted by healthy new sin cells. Stem cell therapy has showed its promising results in the treatment of eyes disorders as well. In United States, the clinics for stem cell therapy are working with the goal of replacing the damaged and dysfunctional tissues/ cells with new healthy and functional ones.
Below are famous Stem cell therapy companies in USA
There is a list of few top companies providing the latest and regenerative stem cell therapies:
1. Adheren Inc.
Adheren is one of the most populous biotechnology company in USA. The focus of company is Cancer immunotherapy. They have core technology platform, antibody cell conjugation (ACC) for the attachment of antibodies to immune cells of the body like T cells. They have well developed Anti-cancer T- cell Therapy using this technology. The methodology followed by Adheren is called ACE-T (antibody Conjugated Effector T cells). This method has been validated both in vitro and in vivo testing which have resulted a promising treatment for a range of cancer types. They are not using Genetically Modified (GM) T cells. They are substantially improving dose-titration capacity.
Resource person: Dr. Matthew Francis
Address: 5858 Horton Street, Suite 255 Emeryville, CA 94608
Official webpage: http://www.adheren.com
2. Cell Design Labs.
Cell Design Labs are renowned labs in USA working on bio therapeutics. They have developed disruptive therapies for the treatment of devastating diseases including cancer. Experts in cell design Lab are working on the immune system stability. They believe that an energetic and powerful immune system can only be able to fight against cancer and other diseases. Cell design lab is on the edge of the new era medicines which will be able to instruct and guide the immune cells of the body to recognize specific targets to eliminate disease or infection.
The next generation anti-cancerous therapies are going to establish in this lab. they are modifying the immune cells of the body to create therapeutic agents which recognize and target the malignant threats in the body. The distinct collection of modules is the heart of Cell design labs. These modules have lethal killing power and target the malignant when deployed to the immune system of the patients. They claim that the living cells are directed to identify a specific threat of the body and neutralize that threat without damaging the healthy cells. Their therapies have power to work against degenerative disorders and other challenging diseases of present era.
Dr. Wendell Lim
Address: 5858 Horton St Suite 240, Emeryville, CA 94608, USA
TEL: +1 510-398-1611
Official webpage: www.celldesignlabs.com
3. Regen Biopharma
Regan BioPharma is a biotechnology based USA company. Their main focus is on the immune-therapies. The objective of company is to develop the novel technologies through phase I and phase II clinical trials. Presently, the Regen BioPharma is providing small molecular facility against cancer. It also establishing its set up for the treatment of blood disorders using small molecules and gene silencing (DiffronC). They are using cellular immunotherapy (dcellvax) for the treatment of cancer. They are modulating the molecular targeting approaches (BORIS) for the processing of Cancer stem cells. They are repairing bone marrow patients using the chemotherapy/ radiotherapy with aplastic anemia.
Address:4700 Spring Street, Suite 304La Mesa, CA 91942. U.S.A.
Telephone: (619) 702-1404
4. IOVANCE Biotherapeutics
Iovance Biotherapeutics are formally known as Lion Biotechnologies. They mainly working on the development and commercialization of immunotherapies against cancer using the Tumor infiltrating Lymphocyctes (TIL) technology. They have adopted the Dr. Steven A. Rosenberg’s adoptive T-cell therapy.the leading product of this company is an autologous and ready-to-infuse cell therapy. They claim that their this product have high level of efficacy for the treatment of metastatic melanoma.
Not only the metastatic melanoma, the carcinoma of the head, and a series tumor types like ovarian, breast, bladder, colorectal and other cancers can also be treated using this technology. Presently, they are developing clinical programs for decreasing the production time and optimizing the distribution processes. The objective of this comapy is to establish TIL therapies which must be accessible, mainline, revolutionary cancer therapy.
Dr. Amod Sarnaik
Address: 999 Skyway RoadSuite 150San Carlos, CA 94070
5. Adicet Bio
Adicet Bio is a pre-clinical biotechnology company focusing on healthcare business since 2014. This private biotechnology company which is designing and developing immunotherapies for cancer and other diseases. The technology, the Adicet Bio using the universal immune cell therapies (uICT). It is working with collaboration with Regeneron Pharmaceticals, Inc. in establishing the next-generation immune-cell therapies. These therapies are disease-specific peptide-MHC complexes which are associated with different disorders.
601 Lexington Avenue, 54th Floor, New York, NY 10022, United States
Founded in 2014
Official website: www.adicetbio.com
6. Adverum Biotechnologies
Adverum Biotechnologies is a gene therapy company. It offers novel medicines for life changing benefits to the patients suffering with devastating diseases and who have limited capital for health treatment. This company in USA is working for next generation Adeno-associated Virus( AAV)- based platforms. Their models are designed to stimulate durable efficacy by the technology of inducing sustained expression of the developed therapeutic proteins. The objective of company is to focus on the patients by clinical expertise and vector optimization, process development, assay development and manufacturing.
1035 O’ Brien Drive, Suite A Menlo Park, CA 94025
Tel: 6502726269, Official webpage: http://adverum.com/
7. Human Longevity, Inc.
A team of leaders in genomics established this company, Human Longevity, Inc. The objective of this company was to empower individuals to modify their life style by shifting their medicines to the preventatives. This data based approach is combining the genotypic and phenotypic data in USA. This data based technology transform the information to new discoveries and new treatments available around the globe like stem cell therapies.
KENNETH J. BLOO
Address: 4570 Excetive Dr san Diego CA 92121
Official website: www.humanlongevity.com/
8. Cellular DynamicsInternational (CDI)
CDI in USA is considered as a world leader in Stem cell therapies. They are holding a large number of induced- pluripotent stem (iPS) cell reforming and banking systems. These cells represent a typical human diversity, various diseases, infections and adverse drug reactions. The grant of $16 million was awarded to CDI by California Institute for Regenerative Medicines (CIRM) to drive three iPS cell lines for diseases like Alzheimer’s disease, autism spectrum disorders, age-related muscular degeneration, familial dilated cardiomyopathy, epilepsy, cerebral palsy, viral hepatitis, non- alcoholic steatohepatitis and idiopathic pulmonary fibrosis.
Address: 525 Science Dr Medison, WI 53711
Official website: https://cellulardynamics.com/
9. VETSTEM BIOPHARMA
VetStem was established in 2002, the goal was to improve the live and health of animals through regenerative medicines. It was the pioneers in USA in providing an adipose- derived stem cells to veterinarians. It holds more than 50 patents in this field. they first time treated horse in 2004 with regenerative cell therapy for the tendon injury of horse that was supposing the career ending. In the start of VetStem, the therapies were not commonly accepted. Alter experts of this company created awareness programs and educated people regarding benefits of stem cells. This company is actively investigating the stem cell therapies for immune mediated and devastating inflammatory diseases. The treatment for organ failure and diseases is the aim of this company.
Address: 12860 Danielson court, suit B Poway, CA 92064
Official website: http:www.vetstem.com
10. OncoMed Pharmaceuticals
OncoMed is a clinical stage – biopharmaceutical company in USA. The focus of this company is to discover and develop the novel therapies for the cancer growth, resistance and metastasis. The have developed ten novel anti-cancerous products and heve enrolled more than 1300 subjects. They are still trying to develop more anti- cancer products. They are working on biologic pathways which drive for tumor growth, metastasis and reocurrance. The experts of this company have identified novel immno-oncology targets in the body and they claim that their evasive techniques and products block these pipelines for cancer growth. As the cancer cells target the immune cells activity of the patients, therefore, their experts are deploying their efforts in manufacturing antibodies which will create bispecifics that will contain two drugs (two in one antibody). This company claims that their products have potential to treat cancer at significant level.
In addition, they have well established patent portfolio which is protecting their novel products and Research and development technologies.
Dr. Paul J. Hastings
Address: 800 Chesapeake Dr, Redwood City, CA 94063, USA
Phone: +1 650-995-8200
Official website: http://www.oncomed.com/
11. Cytori Therapeutics, Inc.
The cytori therapeutics, Inc. is committed to develop and commercialize the cellular therapies. They facilitate the clinical trials for the approved cellular therapies. They are engaged in providing the healthcare facilities. It was established in 2002, since than the scientists working in this company, study and develop the cellular therapies using their NOVAL CELUTION SYSTEM platform. This system deals with the harness of potential stem cells and regenerative cells from adipose tissues. Recently, in 2017, they have developed and have strengthen themselves by acquiring a nano-medicine technology that is the combination of chemotherapy agents, doxorubicin and docetaxel, both with liposomal encapsulation technology. This recent technology has improved the potential of healthcare particularly for the life-threatening diseases. Cytori has 65 full times experts in their company and working simultaneously in Japan, The United Kingdom, and the United States. Cytori is working on the development and improvement of cellular therapies for the patients suffering with Scleroderma.
Christopher J. Calhoun
CYTORI GLOBAL WORLD HEADQUARTERS Cytori Therapeutics, Inc. 3020 Callan Road San Diego, CA 92121, USA Tel: +1.858.458.0900 firstname.lastname@example.org.
Official website: http://www.cytori.com
12. F1 Oncology
F1 oncology has developed a technology to treat the tumor malignancies. They claim that their Chimeric Antigen Receptor (CAR) T cells therapy has delivered remarkable responses against hematologic malignancies. But they are finding challenges in the case of solid tumors. The off tumor toxicity which has a limited range of antigens potential. But recently, they have joined hands with BioAtla, and are now engaged in joint research about CAB potential and response against off tumor toxicity. On the otherside, they have developed a Bid Data Analytics which is a platform where selection of the best can be done among thousands of CARs.
Address: 625 N Flagler Dr #625, West Palm Beach, FL 33401, USA
13. Histogen, Inc.
This company is is working in USA and developing regenerative medicines and innovative cell therapies. The cells are grown under the stimulated embryonic conditions. The focus and purpose of the company is to manufacture the products derived from the company’s own core technology having the mimics the embryonic environment. This maintains the conditions of very low oxygen and suspension, which ultimately stimulates the newly-born cells to produce the vital proteins and other growth factors which are the characteristics of young and developed cells. This technology stimulates the patients stem cells to regenerate new tissues. They have a great market in USA in the sense of commercialization of products.
Dr. Gail Naughton
10655 Sorrento Valley Rd, San Diego, CA 92121, USA
Phone: +1 858-200-9520
Official website: http://www.histogeninc.com
14. ViaCyte, Inc.,
ViaCyte, Inc., is a leader company working in USA for the regenerative medicines. Their innovative regenerative products are based on the differentiation of stem cells into pancreatic beta cells precursors (PEC-01). These products are implemented in a medical device, Encaptra cell delivery system, after implementation these cells matures into endocrine cells that secrete insulin and other hormones and ultimately regulates the glucose level in the blood. The objective of this company is to make patient type 1 and type 2 diabetes free. The successful implantation leads the patient from the acute risks of other health problems as well as from the diabetic associated complications. This company is working under the full supervision of CIRM and JDRF.
Dr. Paul Laikind
Address: 3550 General Atomics Court, San Diego, CA 92121
Phone: 858.455.3708, Fax: 858.455.3962
Official website: http://viacyte.com/
Stratatech is focused on the regenerative medicines which are unique skin substitute products for the therapeutic use. This product was first time made in 2000. These are Human keratinocyte cell lines that produces skin tissues which are almost identical to the human natural skin tissues. This product is considered as a revolutionary in wound care. This company uses their product for the treatment of severe burns, non-healing ulcers and other skin diseases and infections. Their products are second generation products that have great potential for shin burn care. The product has capacity to fight infections, improves blood flow, and increases the overall rate of skin recovery.
Dr. B. Lynn Allen
Address: 510 Charmany Drive, Suite 150, Madison, WI 53719
Phone (608) 441-2750, Fax (608) 441-2757
Official website: http://www.stratatechcorp.com
16. Cell Line Genetics
Cell Line Genetics is a leading provider of cell lines in USA. The cell lines are equally useful in research, translation and clinical applications. Presently, this company is fulfilling the demands of research institutes, biotechnology and Pharmaceutical companies in USA as well as other countries of the world. The widely recognized cell lines of CLG are for the chromosomal anomalies of embryonic and induced pluripotent stem cells and cancer cell lines. Their objective is to deliver accurate, reliable and fast cell lines to satisfy their clients.
Dr. Lorraine Meisner
Phone (608) 441-8160, Fax (608) 441-8162
Email email@example.com, Official website: http://www.clgenetics.com
InGeneronwas founded in 2006. The mission of InGeneron is to progress in health care with their regenerative medicines including stem cell therapies. These cells stimulate the regeneration and self-healing potential of the patient’s body. InGeneron has designed and developed a system that has the capacity to differentiate the regenerative and adipose tissues. Their system is stipulated by International society of Cellular therapy and have great potential to replace and heal damaged tissues. These cell separation technology have great potential to assist the worldwide physicians and veterinarians in the treatment of devastating diseases, orthopedic injuries and cosmetic surgeries.
Dr. Angelo Moesslang
Address: 8205 El Rio St, Houston, TX 77054, USA
Phone: +1 713-440-9900
Official website: http://ingeneron.com/
Athersysis an international biopharmaceutical company. They are engaged in the development of cell therapies including stem cell therapy. They have objective to enhance the quality and health of human life. They have developed a pipeline of products development programs in the control of various diseases. They primarily focus on the regenerative medicines. They aim to discover and develop safer and most effective therapies. They have a leading product MultiStem®, a stem cell product, which has showed promising results for the treatment of inflammatory and immune systems disorders, neurological and cardiovascular diseases. Presently, they are working on the novel pharmaceutical products for obesity and related metabolic disorders.It was established in 1995 and has operations Cleveland, Ohio, Leuven Belgium.
Dr. Gil Van Bokkelen
T: (216) 431-9900, F: (216) 361-9495
19. Chromocell Corporation
Chromocell focus on the quality of consumer products and patients life through breakthrough scientific and technological discoveries. Chromocell have developed its pioneering Chromovert ®Technology which uses rare cells ideally suited for effective screening. Their technologies currently focus on the analgesics and rare diseases. Chromovert ®Technology has proved to be highly effective in repaid identification of potential new drugs candidates. They are worldwide supplier of flavors and natural taste enhancers.
Dr. Christian k.
Address: 685 US-1, North Brunswick Township, NJ 08902, USA
Official website: http://www.chromocell.com
Phone: +1 732-565-1113
20. Neurona Therapeutics
Neurona Therapeutics is a pre-clinical stage biotechnology company. It was founded by four neuroscientists and stem cell therapy pioneers at The University Of California, San Francisco. The company focus on the discovery and development of stem cell therapies for the treatment of neurological diseases. The initial target of this company is to develop specific type of nerve cells / neurons to replace the injured neurons of the patient.
170 Harbor Way, South San Francisco, CA 94080
Email: firstname.lastname@example.org, Official website: http://www.neuronatherapeutics.com/
21. Celyad Inc.
Celyad is a biotechnology company. They focus on the development of stem cell therapies for the life-threatening diseases. They are inspired by natural mechanisms that are used by the human body to fight against infections and diseases. They are working with collaboration of Novartis (Switzerland), ONO Pharmaceuticals Co. limited (Japan) and Dartmouth Collage (USA).
Seaport East 2 Seaport Lane Boston, USA, MA 02210
Ph: + 1 (857) 990-6900, + 1 (857) 233-2971
Official website: https://www.celyad.com/
22. Neovii Biotech NA, Inc.
Neovii Biotech NA, Inc. is an independent and global biopharmaceutical company with a mission of developing novel life-transforming therapies. They have established a stem cell transplantation procedures for many diseases, primarily the blood diseases. During this procedure, the immune system of patient is replaced with healthy donor involving the high dose of chemotherapies and radiations to destroy or mask the cancer cells in doer to receive the stem cells. The donor’s stem cells are then injected in the patient and they migrate to bone marrow, expand and reconstitute the immune system of the patient.
Contact Person: Alexandre Sudarskis
Address: 430 Bedford Street, Suite 195, Lexington, MA 02420, USA
Phone: +1 781 966 3830, Fax: +1 781 373 3766
ViaCord is working in USA since last 25 years. They are providing high quality of Umbilical cord blood stem cells collections for the families. These cord stem cells are the most important part of transplantation surgeries. They have stock of cord blood cells of more than 350,000 newborns and till now they have released more than 360 stem cell units for different transplant or regenerative medicines research. They have also been involved in the research of new stem cells for devastating and life-threatening diseases like cancer, juvenile, diabetes, and heart diseases.
Address: 930 Winter St #2500, Waltham, MA 02451, USA
Phone: +1 866-668-4895
Official website: https://www.viacord.com
24. BrainStom cell Therapeutics
BrainStom cell therapeutics is a biotechnology company in USA. It is developing innovative and autologous stem cell therapies for the neurodegenerative diseases such as amyotrophic Lateral Sclerosis (ALS), Parkinson’s disease, Huntington’s disease, multiple sclerosis and many others. NUROWN ® is a name of technology developed by Brainstom Cell Therapeutics in which mesenchymal stem cells (MSCs) are implanted which after entry in body secrete neurotrophic factors (NTFs) and ultimately promotes the survival of patient’s neurons. This procedure helps in the treatment of neurodegenerative diseases.
Address: Three University Plaza Drive, Suite 320, Hackensack, NJ 07601
Official website: http://www.brainstorm-cell.com/
Celvive is a biopharmaceutical company founded in 2011. It is working in USA with current focus of the development of therapies and use of autologoue stem cells for regenerative medicines. The initial procedures involve the neural regeneration of patients suffering with spinal cord injury (SCI). They have adopted a new approach of closed bag system for the isolation of specific adult stem cells from the patient’s own bone marrow to treat the SCI.
Address: Tower II, 120 Albany St #850, New Brunswick, NJ 08901, USA
Phone: +1 908-731-6610
Official website: http://www.celvive.com
Author: Ammara Hassan
Published on: Dec 3, 2017